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KMID : 0616120110420020127
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Korean Journal of Pharmacognosy
2011 Volume.42 No. 2 p.127 ~ p.137
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Phytochemical Studies on Rehmanniae Radix
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Lee So-Young
Yean Min-Hye
Kim Ju-Sun
Lee Je-Hyeon
Kang Sam-Sik
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Abstract
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Twenty-four compounds were isolated from the 70% ethanolic extract of Rehmanniae Radix (Scrophulariaceae) cultivated in Ubo-myeon, Gunwi-gun, Gyeongbuk province, Korea and their structures were identified as four iridoids [6-O-(4’’-O--L-rhamnopyranosyl) vanilloyl ajugol (17), ajugol (18), aucubin (19), and catalpol (20)], three phenethyl alcohol glycosides [decaffeoyl acteoside (15), isoacteoside (16), and acteoside (21)], five sugar derivatives [ethyl -D-fructofuranoside (7), eleutheroside C (14), mannitol (22), raffinose (23), and stachyose (24)], two terpenoids [remophilanetriol (4) and glutinolic acid (11)], a lignan, paulownin (2), and eight others [-sitosterol (1), daucosterol (6), monopalmitin (3), pinellic acid (9), uracil (5), adenosine (12), jio-cerebroside (10), aeginetic acid 5-O--D-quinovoside (8), aeginetoyl ajugol 5’’-O--D-quinovoside (13)]. The chemical structures of these compounds were identified on the basis of spectroscopic methods and comparison with literature values. Among these compounds, paulownin (2), monopalmitin (3), uracil (5), daucosterol (6), ethyl -D-fructo-furanoside (7), and eleutheroside C (14) were isolated from this plant for the first time.
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KEYWORD
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Rehmannia glutinosa Liboschitz ex Steudel, Scrophulariaceae, Isolation and identification
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